Description

Ipi-926 Hydrochloride is a high-purity, small molecule inhibitor targeting the Hedgehog signaling pathway. This compound is critical for advanced pharmaceutical research and development, particularly in oncology. It is primarily utilized by research institutions, pharmaceutical companies, and CROs for preclinical studies and drug discovery programs focused on cancer therapeutics.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel anticancer drugs.
• Preclinical Studies: For in vitro and in vivo investigation of Hedgehog pathway inhibition and its effects on tumor growth and metastasis.
• Biochemical Assays: Used as a potent and selective tool compound in high-throughput screening and mechanism-of-action studies.
• Academic Research: Enables fundamental research into developmental biology and the role of signaling pathways in disease.

Basic Information

Product Name	Ipi-926 Hydrochloride
CAS No.	1169829-40-6
Molecular Formula	C31H41ClN2O5 • HCl
Molecular Weight	593.04 g/mol
Synonyms	IPI-926 HCl; Saridegib Hydrochloride; Hedgehog pathway inhibitor IPI-926 HCl; (3S,3'S,5'R,6'S)-6'-[(2S)-2-(1H-Indol-3-yl)propanoyl]-N-methyl-3'-(2-methylpropyl)-2-oxo-5'-phenyl-1',2',3',5',6',7'-hexahydrospiro[indole-3,4'-pyrrolo[3,2-c]pyridine]-2-one hydrochloride
EINECS	Contact for details

Quality Control

Our Ipi-926 Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications. We support research and development with material suitable for use under cGMP guidelines for preclinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.