Description

(2S)-2-Amino-6-{[(2-Azidoethoxy)Carbonyl]Amino}Hexanoic Acid is a specialized, non-natural amino acid derivative featuring a reactive azidoethyl carbamate side chain. This compound matters as a versatile building block in chemical biology and pharmaceutical research, enabling the synthesis of complex biomolecules through bioorthogonal click chemistry. It is primarily needed by researchers and manufacturers in the fields of bioconjugation, peptide synthesis, and proteomics for developing novel drug conjugates, diagnostic probes, and advanced materials.

Application

• Bioconjugation and Click Chemistry: Serves as a key intermediate for the site-specific modification of peptides, proteins, and antibodies via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (SPAAC).
• Pharmaceutical Research: Used in the synthesis of novel drug candidates, antibody-drug conjugates (ADCs), and targeted therapeutics.
• Proteomics and Chemical Biology: Employed as a functionalized amino acid for metabolic labeling, activity-based protein profiling (ABPP), and the study of protein function.
• Peptide Synthesis: Incorporated into custom peptide sequences to introduce unique handles for downstream labeling, crosslinking, or immobilization.
• Material Science: Utilized in the development of functionalized polymers, hydrogels, and surfaces for biomedical and diagnostic applications.
• Diagnostic Reagent Development: Acts as a precursor for fluorescent or affinity tags used in imaging and detection assays.

Basic Information

Product Name	(2S)-2-Amino-6-{[(2-Azidoethoxy)Carbonyl]Amino}Hexanoic Acid
CAS No.	1167421-25-1
Molecular Formula	C10H18N6O4
Molecular Weight	286.29 g/mol
Synonyms	N6-[(2-Azidoethoxy)carbonyl]-L-lysine; L-Lysine, N6-[(2-azidoethoxy)carbonyl]-; Azido-PEG1-C2-Lysine; Nε-[(2-Azidoethoxy)carbonyl]-L-lysine; 6-[(2-Azidoethoxy)carbonylamino]-L-norleucine; Click Chemistry Amino Acid; AHAz derivative; Azidoethyl Carbamate Lysine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide high-purity material suitable for research and development, with identity and purity verified by advanced analytical techniques. Certificates of Analysis (COA) detailing HPLC purity, chiral purity, and spectroscopic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Chiral Purity (HPLC)	≥98% ee
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.