Description

1-Amino-11-Azido-3,6,9-Trioxaundecane is a specialized heterobifunctional polyethylene glycol (PEG) derivative, featuring a primary amine and an azide group separated by a triethylene glycol spacer. This compound is engineered for high-value applications in bioconjugation and materials science, enabling efficient, orthogonal "click chemistry" reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostics, and advanced polymer sectors for creating targeted drug delivery systems, functionalized surfaces, and novel biomaterials.

Application

• Bioconjugation and Linker Chemistry: Serves as a versatile heterobifunctional crosslinker for coupling biomolecules (e.g., proteins, peptides, oligonucleotides) to other entities via amine-reactive and azide-alkyne cycloaddition chemistries.
• PEGylation Reagent: Used to introduce PEG chains with a reactive azide handle onto amine-containing drugs or surfaces to improve solubility, stability, and pharmacokinetics.
• Click Chemistry Scaffold: The azide group facilitates copper-catalyzed (CuAAC) or strain-promoted (SPAAC) alkyne-azide cycloadditions, a cornerstone of modern bioorthogonal labeling and polymer synthesis.
• Surface Functionalization: Employed to modify nanoparticles, biosensors, and chromatographic media with amine-reactive or clickable groups for specific binding or capture.
• Polymer and Dendrimer Synthesis: Acts as a building block for constructing functionalized polymers, hydrogels, and dendritic structures with precise architecture.
• Diagnostic Probe Development: Utilized in the synthesis of contrast agents, fluorescent probes, and other diagnostic tools where controlled attachment of signaling molecules is required.

Basic Information

Product Name	1-Amino-11-Azido-3,6,9-Trioxaundecane
CAS No.	1162336-72-2
Molecular Formula	C11H24N4O3
Molecular Weight	260.33 g/mol
Synonyms	Azido-PEG3-amine; 11-Azido-3,6,9-trioxaundecan-1-amine; 3,6,9-Trioxaundecane-1,11-diamine, 11-azido-; Amino-PEG3-azide; N1-(2-Azidoethoxy)ethyl)-N3-amino-3,6-dioxaoctane; Heterobifunctional PEG, NH2-PEG3-N3; Azido-PEG-NH2 (MW ~260)
EINECS	Contact for details

Quality Control

Our 1-Amino-11-Azido-3,6,9-Trioxaundecane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic and moisture-sensitive nature, containers should be sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.