Description

Boc-Tota-N3 is a specialized azide-functionalized building block used in advanced organic synthesis and bioconjugation chemistry. This compound is critical for researchers and manufacturers requiring high-purity intermediates for click chemistry applications, particularly in the development of pharmaceuticals and bioactive probes. It is primarily utilized by professionals in pharmaceutical R&D, agrochemical discovery, and materials science for constructing complex molecular architectures.

Application

• Click Chemistry Reagent: Serves as a key precursor for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create triazole linkages.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, especially in targeted drug delivery systems.
• Bioconjugation: Enables site-specific labeling and modification of proteins, antibodies, and other biomolecules for diagnostic and therapeutic applications.
• Polymer & Materials Science: Functionalizes polymers and surfaces to introduce bioactive or responsive properties.
• Chemical Biology Probe Development: Utilized to create activity-based probes for studying enzyme function and cellular pathways.
• Agrochemical Synthesis: Acts as a building block for novel crop protection agents and herbicides.

Basic Information

Product Name	Boc-Tota-N3
CAS No.	1162070-33-8
Molecular Formula	C₁₄H₂₆N₄O₄
Molecular Weight	314.38 g/mol
Synonyms	tert-Butyl (2S,4R)-4-azido-1-[(tert-butoxy)carbonyl]-2-pyrrolidinecarboxylate; (2S,4R)-1-(tert-Butoxycarbonyl)-4-azidopyrrolidine-2-carboxylic acid tert-butyl ester; Boc-4-azido-L-proline-OtBu; Boc-trans-4-azido-L-proline-OtBu; Boc-Tota(azido)-OtBu; Azido-Proline(Boc)-OtBu; 4-Azidoproline derivative
EINECS	Contact for details

Quality Control

Our Boc-Tota-N3 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a well-ventilated area and away from sources of heat and ignition due to the azide functional group.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.