Description

4-Cyano-3-Methylbenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value proposition lies in enabling the efficient introduction of the 4-cyano-3-methylbenzoyl moiety into target molecules, facilitating the development of complex chemical architectures. This intermediate is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to create novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a substituted benzoyl group.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the cyano and acyl chloride functionalities enable specific biological activity.
• Liquid Crystal & OLED Material Production: Serves as a building block for advanced electronic materials, including liquid crystal displays and organic light-emitting diodes.
• Polymer & Resin Modification: Employed to introduce functional side chains into polymers, enhancing properties like thermal stability, adhesion, or solubility.
• Dyestuff & Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and high-performance pigments.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing biaryl systems.
• Peptide & Protein Research: Can be used as a coupling agent or for modifying amino acid side chains in biochemical research.
• Custom Synthesis & R&D: Essential for contract research organizations and academic labs exploring new chemical entities and reaction pathways.

Basic Information

Item	Details
Product Name	4-Cyano-3-Methylbenzoyl Chloride
CAS No.	1160759-52-3
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	3-Methyl-4-cyanobenzoyl chloride; 4-Cyano-m-toluoyl chloride; 4-Cyano-3-methylbenzoic acid chloride; 3-Methyl-4-cyanobenzoic acid chloride; (4-Cyano-3-methylphenyl)carbonyl chloride; 4-Cyanotoluoyl chloride; 3-Methyl-4-cyanobenzoylchloride; 4-Cyano-3-methyl-benzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Cyano-3-Methylbenzoyl Chloride is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for sensitive synthesis applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality system is designed to support GMP and ISO-guided manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a cool, dry place with minimal exposure to atmospheric humidity. For long-term stability, store at controlled room temperature (15-25°C) under an inert atmosphere such as nitrogen or argon. Keep away from moisture, strong bases, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF Titration)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.