Description

[2,3-Dichloro-5-(Trifluoromethyl)-4-Pyridinyl]-Methanol is a high-value, multi-functional pyridine derivative serving as a critical synthetic intermediate in advanced chemical manufacturing. Its unique halogenated and trifluoromethylated structure makes it an essential building block for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated pyridine core.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and inhibitors used in biochemical and pharmacological research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized fluorinated heterocycles.

Basic Information

Product Name	[2,3-Dichloro-5-(Trifluoromethyl)-4-Pyridinyl]-Methanol
CAS No.	1160474-70-3
Molecular Formula	C7H4Cl2F3NO
Molecular Weight	246.01 g/mol
Synonyms	(2,3-Dichloro-5-(trifluoromethyl)pyridin-4-yl)methanol; 4-Pyridinemethanol, 2,3-dichloro-5-(trifluoromethyl)-; 2,3-Dichloro-5-trifluoromethyl-4-pyridinemethanol; 2,3-Dichloro-5-(trifluoromethyl)pyridine-4-methanol; 4-(Hydroxymethyl)-2,3-dichloro-5-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our production of [2,3-Dichloro-5-(Trifluoromethyl)-4-Pyridinyl]-Methanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.