Description

2-(5-Methyl-2-Furyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive organic intermediate characterized by its quinoline core functionalized with a furan ring and an acid chloride group. This compound is of significant value in advanced organic synthesis, serving as a versatile building block for constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the biological activity of the quinoline and furan motifs.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating novel nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Employed in the synthesis of organic semiconductors, light-emitting materials, or metal-organic frameworks (MOFs) due to its conjugated structure.
• Fluorescent Probe Development: The quinoline scaffold makes it suitable for constructing fluorescent markers and sensors for biological or chemical detection.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	2-(5-Methyl-2-Furyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160264-92-5
Molecular Formula	C16H12ClNO2
Molecular Weight	285.73 g/mol
Synonyms	2-(5-Methylfuran-2-yl)quinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(5-methyl-2-furanyl)-; 2-(5-Methyl-2-furyl)-4-quinolinecarbonyl chloride; Quinoline-4-carbonyl chloride, 2-(5-methyl-2-furyl)-; 2-(5-Methylfuran-2-yl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(5-Methyl-2-Furyl)Quinoline-4-Carbonyl Chloride is manufactured and tested under strict quality management protocols. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.