Description

2-(5-Chloro-2-Thienyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive organic intermediate of significant importance in advanced chemical synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Material Science: Serves as a precursor for the synthesis of functional organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology: Employed in the creation of molecular probes and tool compounds for studying biological processes.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and contract research organizations (CROs) exploring new chemical entities.

Basic Information

Product Name	2-(5-Chloro-2-Thienyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160264-90-3
Molecular Formula	C14H7Cl2NOS
Molecular Weight	308.18 g/mol
Synonyms	5-Chloro-2-(4-chlorocarbonylquinolin-2-yl)thiophene; 2-(5-Chlorothiophen-2-yl)quinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 2-(5-chloro-2-thienyl)-; 2-(5-Chloro-2-thienyl)-4-quinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(5-Chloro-2-Thienyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.