Description

2-(2,5-Dimethoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-value, reactive chemical intermediate belonging to the quinoline class of heterocyclic compounds. This compound matters for its role as a versatile building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various disease pathways.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides due to the bioactive quinoline core structure.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The quinoline scaffold is utilized in the design and synthesis of fluorescent dyes and molecular probes for biochemical sensing and imaging.
• Material Science: Intermediate for the production of advanced organic electronic materials and polymers with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up services.

Basic Information

Product Name	2-(2,5-Dimethoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160264-87-8
Molecular Formula	C19H14ClNO3
Molecular Weight	339.77 g/mol
Synonyms	2-(2,5-Dimethoxyphenyl)-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(2,5-dimethoxyphenyl)-; 2-(2,5-Dimethoxyphenyl)quinoline-4-carboxylic acid chloride; 2-(2,5-Dimethoxyphenyl)-4-quinolinecarboxylic acid chloride; 1160264-87-8
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dimethoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in common organic solvents (DCM, DMF, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.