Description

2-(4-Isobutoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters because its unique quinoline-carbonyl chloride structure serves as a critical building block for creating complex molecules with specific functionalities. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, particularly for anti-malarial, anti-cancer, and anti-inflammatory applications.
• Agrochemical Synthesis: Building block for developing advanced pesticides and herbicides, leveraging the biological activity of the quinoline scaffold.
• Material Science Research: Used in the creation of organic ligands for metal-organic frameworks (MOFs) and functional polymers.
• Dye and Pigment Intermediate: Serves in the synthesis of specialized quinoline-derived colorants and fluorescent markers.
• Academic & R&D: Fundamental reagent in university and corporate research laboratories for methodological development and exploring new chemical spaces.
• Custom Synthesis: Starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	2-(4-Isobutoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160264-84-5
Molecular Formula	C20H18ClNO2
Molecular Weight	339.82 g/mol
Synonyms	2-(4-Isobutoxyphenyl)-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-[4-(2-methylpropoxy)phenyl]-; 2-[4-(Isobutoxy)phenyl]quinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 2-(4-isobutoxyphenyl)-; 1160264-84-5; 2-(4-(2-Methylpropoxy)phenyl)quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(4-Isobutoxyphenyl)Quinoline-4-Carbonyl Chloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.