Description

2-(2-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific quinoline-based scaffolds into their target compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing quinoline or isopropoxyphenyl pharmacophores for therapeutic applications.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the quinoline structure can contribute to biological activity.
• Material Science & OLED Development: Serves as a building block for creating organic light-emitting diode (OLED) materials and other advanced functional materials due to its conjugated aromatic system.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.
• Fluorescent Probe & Dye Synthesis: Utilized as a core structure for developing fluorescent markers, sensors, and specialized dyes for analytical and diagnostic applications.
• Academic & Contract Research: A valuable reagent for universities and contract research organizations (CROs) conducting exploratory chemistry and method development.

Basic Information

Product Name	2-(2-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160264-82-3
Molecular Formula	C19H16ClNO2
Molecular Weight	325.79 g/mol
Synonyms	2-(2-Isopropoxyphenyl)-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-[2-(1-methylethoxy)phenyl]-; 2-[2-(Propan-2-yloxy)phenyl]quinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 2-(2-isopropoxyphenyl)-; 2-(2-Isopropoxyphenyl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-(2-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.