Description

2-(4-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a versatile building block for constructing complex heterocyclic frameworks, particularly in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is essential for research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinoline-based drug candidates, potentially for therapeutic areas like oncology, anti-infectives, and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, or fungicides that leverage the quinoline scaffold for bioactivity.
• Material Science Research: Serves as a building block for creating advanced organic materials, such as ligands for catalysts, organic semiconductors, or fluorescent dyes and sensors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D programs.

Basic Information

Product Name	2-(4-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160264-81-2
Molecular Formula	C19H16ClNO2
Molecular Weight	325.79 g/mol
Synonyms	2-(4-Isopropoxyphenyl)-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-[4-(1-methylethoxy)phenyl]-; 2-(p-Isopropoxyphenyl)quinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 2-(4-isopropoxyphenyl)-; 1160264-81-2
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Isopropoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical syntheses. We provide comprehensive analytical documentation, including a detailed Certificate of Analysis (COA) with each shipment, verifying identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.