Description

2-(4-Ethoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-purity organic intermediate, specifically an acid chloride derivative of a quinoline carboxylic acid. This compound is a critical building block for the synthesis of more complex molecules, offering a reactive site for amide bond formation and other nucleophilic substitutions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for potential therapeutic agents.
• Agrochemical Synthesis: Used as a building block for developing advanced pesticides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent probes or affinity labels for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-(4-Ethoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160264-75-4
Molecular Formula	C₁₈H₁₄ClNO₂
Molecular Weight	311.76 g/mol
Synonyms	4-Quinolinecarbonyl chloride, 2-(4-ethoxyphenyl)-; 2-(p-Ethoxyphenyl)-4-quinolinecarbonyl chloride; 2-(4-Ethoxyphenyl)quinoline-4-carboxylic acid chloride; Quinoline-4-carbonyl chloride, 2-(4-ethoxyphenyl)-; 1160264-75-4; 2-(4-Ethoxyphenyl)-4-quinolylcarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(4-Ethoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.