Description

2-(4-Isobutylphenyl)Quinoline-4-Carbonyl Chloride is a high-value, reactive chemical intermediate primarily used in advanced organic synthesis. Its core value lies in its role as a versatile building block for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting inflammation and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its quinoline core structure.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The quinoline scaffold is utilized in the design of fluorescent dyes and sensors for biological imaging and diagnostics.
• Material Science: Intermediate for the synthesis of organic electronic materials and advanced polymers with specific optical or electronic properties.
• Academic & Contract Research: A critical reagent for method development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	2-(4-Isobutylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160264-74-3
Molecular Formula	C20H18ClNO
Molecular Weight	323.82 g/mol
Synonyms	2-(4-Isobutylphenyl)quinoline-4-carbonyl chloride; 4-Isobutyl-2-phenylquinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 2-(4-isobutylphenyl)-; 2-(p-Isobutylphenyl)-4-quinolinecarbonyl chloride; 1160264-74-3; 2-(4-(2-Methylpropyl)phenyl)quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 2-(4-Isobutylphenyl)Quinoline-4-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.