Description

2-(3,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its role as a versatile building block for constructing complex heterocyclic frameworks, particularly in the development of specialized fine chemicals and active pharmaceutical ingredients (APIs). This compound is critically needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors, antimicrobial agents, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the quinoline scaffold for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Functional Material Research: Employed in the synthesis of organic semiconductors, light-emitting materials, or fluorescent dyes due to the conjugated quinoline system.
• Academic and Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new chemical entities and reaction methodologies.
• Custom Synthesis and Scale-up: Supplied for custom manufacturing projects requiring precise, high-quality intermediates for pilot plant and commercial-scale production.

Basic Information

Product Name	2-(3,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160264-71-0
Molecular Formula	C18H14ClNO
Molecular Weight	295.76 g/mol
Synonyms	2-(3,4-Dimethylphenyl)-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(3,4-dimethylphenyl)-; 2-(3,4-Dimethylphenyl)quinoline-4-carboxylic acid chloride; 2-(3,4-Xylyl)quinoline-4-carbonyl chloride; 1160264-71-0; Quinoline-4-carbonyl chloride, 2-(3,4-dimethylphenyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-(3,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with each shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.