Description

7-Chloro-2-(3-Isopropoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within the fields of oncology and anti-infective research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for quinoline-based drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Chemical Synthesis Building Block: The reactive acid chloride group enables amide bond formation, facilitating the construction of complex molecular architectures.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science: Can serve as a monomer or functionalizing agent in the synthesis of specialized polymers and advanced materials.

Basic Information

Product Name	7-Chloro-2-(3-Isopropoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160263-84-2
Molecular Formula	C21H19Cl2NO2
Molecular Weight	388.29 g/mol
Synonyms	4-Chlorocarbonyl-7-chloro-2-(3-isopropoxyphenyl)-8-methylquinoline; 7-Chloro-2-(3-isopropoxyphenyl)-8-methyl-4-quinolinecarbonyl chloride; 8-Methyl-7-chloro-2-(3-isopropoxyphenyl)quinoline-4-carbonyl chloride; 2-(3-Isopropoxyphenyl)-7-chloro-8-methylquinoline-4-carbonyl chloride; CAS 1160263-84-2
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-(3-Isopropoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.