Description

7-Chloro-2-(4-Isopropoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate with a reactive acid chloride group. This compound matters for its critical role as a key building block in the synthesis of complex organic molecules, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used as a building block for developing advanced active ingredients in crop protection products, such as herbicides and fungicides.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds due to its quinoline core structure.
• Custom Synthesis and Contract Manufacturing: A key reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals for clients.
• Academic and Industrial R&D: Essential for exploratory chemistry in both academic institutions and corporate R&D laboratories for discovering new chemical entities.

Basic Information

Product Name	7-Chloro-2-(4-Isopropoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160263-82-0
Molecular Formula	C21H19Cl2NO2
Molecular Weight	388.29 g/mol
Synonyms	4-Quinolinecarbonyl chloride, 7-chloro-2-[4-(1-methylethoxy)phenyl]-8-methyl-; 7-Chloro-2-(4-isopropoxyphenyl)-8-methyl-4-quinolinecarbonyl chloride; 2-(4-Isopropoxyphenyl)-7-chloro-8-methylquinoline-4-carbonyl chloride; 7-Chloro-8-methyl-2-(4-propan-2-yloxyphenyl)quinoline-4-carbonyl chloride; 1160263-82-0; Quinoline-4-carbonyl chloride derivative
EINECS	Contact for details

Quality Control

Our production of 7-Chloro-2-(4-Isopropoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and batch-to-batch consistency, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and organic solvents. Ensure the storage area is well-ventilated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.