Description

8-Chloro-2-(4-Propoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is critical for the synthesis of complex molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily sought after by R&D laboratories and manufacturers in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in the development of quinoline-based therapeutics.
• Agrochemical Research: Used in the creation of novel pesticides and herbicides, leveraging its complex heterocyclic structure for biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Synthesis: Employed in academic and industrial research as a versatile reagent for introducing the quinoline-4-carbonyl moiety into target molecules.
• Ligand & Catalyst Development: Utilized in the preparation of complex ligands for metal-organic frameworks (MOFs) or catalytic systems.

Basic Information

Product Name	8-Chloro-2-(4-Propoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-77-3
Molecular Formula	C19H15Cl2NO2
Molecular Weight	360.23 g/mol
Synonyms	8-Chloro-2-(4-propoxyphenyl)quinoline-4-carbonyl chloride; 2-(4-Propoxyphenyl)-8-chloroquinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 8-chloro-2-(4-propoxyphenyl)-; 1160263-77-3; 8-Chloro-2-(4-propoxy-phenyl)-quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-(4-Propoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and cGMP starting material standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.