Description

8-Chloro-2-(2-Ethoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive carbonyl chloride and halogenated quinoline structure. This compound matters for its critical role in facilitating complex molecular synthesis, enabling the construction of advanced pharmacophores and functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in creating advanced herbicides, fungicides, and pesticides that leverage the bioactivity of the quinoline scaffold.
• Material Science: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials due to its planar, aromatic structure.
• Chemical Synthesis: Acts as a versatile acylating and coupling agent in organic synthesis, particularly in peptide-mimetic and heterocyclic chemistry.
• Dye & Pigment Industry: Intermediate for the production of specialized quinoline-derived dyes and fluorescent markers.

Basic Information

Product Name	8-Chloro-2-(2-Ethoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-75-1
Molecular Formula	C19H13Cl2NO2
Molecular Weight	358.22 g/mol
Synonyms	8-Chloro-2-(2-ethoxyphenyl)-4-quinolinecarbonyl chloride; 2-(2-Ethoxyphenyl)-8-chloroquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 8-chloro-2-(2-ethoxyphenyl)-; 1160263-75-1; 8-Chloro-2-(2-ethoxyphenyl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 8-Chloro-2-(2-Ethoxyphenyl)Quinoline-4-Carbonyl Chloride adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flame, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.