Description

7-Chloro-8-Methyl-2-(4-Methylphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its functional groups, which make it a versatile building block for constructing complex heterocyclic frameworks. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting specific enzyme pathways where the quinoline core is active.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides, leveraging its halogenated quinoline structure.
• Material Science Research: Serves as a monomer or functional unit in the development of advanced organic electronic materials, such as OLEDs or sensors.
• Ligand and Catalyst Development: The quinoline nitrogen and carbonyl chloride group allow for the creation of novel chelating ligands for metal catalysis.
• Fluorescent Dye and Probe Synthesis: Acts as a foundational structure for developing new fluorescent markers and biological imaging agents.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring complex quinoline derivatives.

Basic Information

Product Name	7-Chloro-8-Methyl-2-(4-Methylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-52-4
Molecular Formula	C19H13Cl2NO
Molecular Weight	342.22 g/mol
Synonyms	4-Chlorocarbonyl-7-chloro-8-methyl-2-p-tolylquinoline; 2-(4-Methylphenyl)-7-chloro-8-methylquinoline-4-carbonyl chloride; 7-Chloro-8-methyl-2-(4-methylphenyl)-4-quinolinecarbonyl chloride; 7-Chloro-8-methyl-2-(p-tolyl)quinoline-4-carbonyl chloride; 2-(p-Tolyl)-7-chloro-8-methylquinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 7-chloro-8-methyl-2-(4-methylphenyl)-; 1160263-52-4
EINECS	Contact for details

Quality Control

Our production of 7-Chloro-8-Methyl-2-(4-Methylphenyl)Quinoline-4-Carbonyl Chloride adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, impurity profile, and physical characteristics is provided with each shipment to guarantee compliance with your research and process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) and separated from strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.