Description

6-Chloro-2-(3-Propoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical building block primarily used in advanced organic synthesis. Its core value lies in its dual reactive sites, the acid chloride and chloro-quinoline groups, which enable efficient construction of complex molecular architectures. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and anti-cancer agent research.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in the creation of organic semiconductors, liquid crystals, and advanced polymers due to the quinoline core.
• Dye and Pigment Intermediate: Serves as a precursor for synthesizing specialized quinoline-based dyes and fluorescent markers.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for biological imaging and assay development.
• Custom Synthesis Projects: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.

Basic Information

Product Name	6-Chloro-2-(3-Propoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-42-2
Molecular Formula	C20H15Cl2NO2
Molecular Weight	372.25 g/mol
Synonyms	6-Chloro-2-(3-propoxyphenyl)quinoline-4-carbonyl chloride; 2-(3-Propoxyphenyl)-6-chloroquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 6-chloro-2-[3-(propoxy)phenyl]-; 1160263-42-2; CPQC; 6-Chloro-2-(3-propoxy-phenyl)-quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-2-(3-Propoxyphenyl)Quinoline-4-Carbonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.