Description

6-Chloro-2-(2-Ethoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, bifunctional organic intermediate featuring both a reactive acid chloride group and a halogenated quinoline core. This compound matters for its critical role as a versatile building block in the synthesis of complex, biologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Building block for developing advanced crop protection chemicals and herbicides with specific activity profiles.
• Material Science Research: Used in the creation of functionalized organic ligands for metal-organic frameworks (MOFs) or advanced polymers.
• Chemical Biology Probes: Serves as a starting material for synthesizing fluorescent tags or molecular probes for diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and process development of client-specific molecules.

Basic Information

Product Name	6-Chloro-2-(2-Ethoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-36-4
Molecular Formula	C19H13Cl2NO2
Molecular Weight	358.22 g/mol
Synonyms	2-(2-Ethoxyphenyl)-6-chloroquinoline-4-carbonyl chloride; 6-Chloro-2-(2-ethoxyphenyl)-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 6-chloro-2-(2-ethoxyphenyl)-; 6-Chloro-2-(2-ethoxyphenyl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(2-Ethoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.