Description

6-Chloro-2-(2,5-Dimethoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive carbonyl chloride and halogenated quinoline core. This compound is critical for synthesizing complex molecules where precise structural modification is required. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinoline-based drug candidates, including potential antivirals, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in creating advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a precursor for functional dyes, organic semiconductors, and metal-organic frameworks (MOFs) due to its conjugated quinoline system.
• Chemical Synthesis: An essential reagent for introducing the 2-(2,5-dimethoxyphenyl)quinoline scaffold into larger molecules via amide or ester bond formation.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and exploring new chemical reactions.

Basic Information

Product Name	6-Chloro-2-(2,5-Dimethoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-32-0
Molecular Formula	C19H15Cl2NO3
Molecular Weight	376.23 g/mol
Synonyms	6-Chloro-2-(2,5-dimethoxyphenyl)quinoline-4-carbonyl chloride; 2-(2,5-Dimethoxyphenyl)-6-chloroquinoline-4-carbonyl chloride; 4-Chlorocarbonyl-6-chloro-2-(2,5-dimethoxyphenyl)quinoline; Quinoline-4-carbonyl chloride, 6-chloro-2-(2,5-dimethoxyphenyl)-; 1160263-32-0
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-2-(2,5-Dimethoxyphenyl)Quinoline-4-Carbonyl Chloride adheres to stringent in-process controls and final batch testing to ensure consistent purity and performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the exacting standards required for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.