Description

6-Chloro-2-(2,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional organic intermediate characterized by its reactive carbonyl chloride group and complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of advanced pharmaceutical agents and functional materials, where precise molecular architecture is paramount. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in developing novel quinoline-based compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the synthesis of chemical probes to study biological processes.
• Dye & Pigment Industry: Functions as an intermediate for creating complex heterocyclic dyes and pigments with specific light-absorption properties.

Basic Information

Product Name	6-Chloro-2-(2,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-13-7
Molecular Formula	C19H13Cl2NO
Molecular Weight	342.22 g/mol
Synonyms	2,4-Dimethyl-6-chloroquinoline-4-carbonyl chloride; 4-Chlorocarbonyl-6-chloro-2-(2,4-dimethylphenyl)quinoline; 6-Chloro-2-(2,4-dimethylphenyl)-4-quinolinecarbonyl chloride; Quinoline-4-carbonyl chloride, 6-chloro-2-(2,4-dimethylphenyl)-; 1160263-13-7
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-2-(2,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride adheres to stringent in-process controls and final batch testing to ensure consistent purity and performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to support cGMP and ISO standards for traceability and reliability, making this intermediate suitable for demanding regulatory applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.