Description

6-Chloro-2-(5-Ethyl-2-Thienyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive carbonyl chloride and quinoline-thiophene hybrid structure. This compound is essential for facilitating complex organic synthesis, particularly in the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing novel molecular architectures.

Application

This versatile intermediate serves as a critical building block in several advanced chemical syntheses. Key application areas include:

• Pharmaceutical Intermediate: Core precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Acts as a monomer or precursor for creating organic semiconductors, liquid crystals, and photoactive polymers.
• Complex Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Serves as a key component in the synthesis of advanced quinoline-based colorants and fluorescent markers.

Basic Information

Product Name	6-Chloro-2-(5-Ethyl-2-Thienyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-09-1
Molecular Formula	C₁₇H₁₁Cl₂NOS
Molecular Weight	348.25 g/mol
Synonyms	6-Chloro-2-(5-ethylthiophen-2-yl)quinoline-4-carbonyl chloride; 2-(5-Ethyl-2-thienyl)-6-chloro-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 6-chloro-2-(5-ethyl-2-thienyl)-; 1160263-09-1; 6-Chloro-2-(5-ethyl-2-thienyl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-2-(5-Ethyl-2-Thienyl)Quinoline-4-Carbonyl Chloride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.