Description

6-Chloro-2-(5-Methyl-2-Thienyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical building block crucial for advanced organic synthesis. Its core value lies in its dual reactive sites, making it an essential intermediate for constructing complex heterocyclic molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinoline-based drug candidates, particularly in therapeutic areas targeting infectious diseases and oncology.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the bioactivity of the quinoline-thiophene scaffold.
• Material Science Precursor: Serves as a monomer or precursor for creating specialized organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic libraries via amidation, esterification, or cross-coupling reactions following acyl chloride activation.
• Ligand Synthesis: Useful for preparing chelating ligands in coordination chemistry and catalysis due to the presence of nitrogen and sulfur donor atoms.

Basic Information

Product Name	6-Chloro-2-(5-Methyl-2-Thienyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160263-07-9
Molecular Formula	C₁₆H₉Cl₂NOS
Molecular Weight	334.22 g/mol
Synonyms	6-Chloro-2-(5-methylthiophen-2-yl)quinoline-4-carbonyl chloride; 2-(5-Methyl-2-thienyl)-6-chloro-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 6-chloro-2-(5-methyl-2-thienyl)-; 1160263-07-9; 6-Chloro-2-(5-methyl-2-thienyl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(5-Methyl-2-Thienyl)Quinoline-4-Carbonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.