Description

2-(3,4-Dimethoxyphenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is of significant value in organic synthesis, serving as a critical building block for the construction of complex molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex quinoline-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Organic Synthesis: Employed in amide coupling reactions and other transformations where an activated carboxylic acid derivative is required.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel crop protection agents and pesticides.
• Material Science Research: Investigated as a monomer or precursor for the creation of specialty polymers and functional materials.

Basic Information

Product Name	2-(3,4-Dimethoxyphenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride
CAS No.	1160262-85-0
Molecular Formula	C21H20ClNO3
Molecular Weight	369.84 g/mol
Synonyms	6,8-Dimethyl-2-(3,4-dimethoxyphenyl)quinoline-4-carbonyl chloride; 2-(3,4-Dimethoxyphenyl)-6,8-dimethyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(3,4-dimethoxyphenyl)-6,8-dimethyl-; 1160262-85-0
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dimethoxyphenyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.