Description

7,8-Dimethyl-2-(2-Thienyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters because it serves as a critical building block for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the quinoline-thiophene scaffold for bioactivity.
• Material Science Research: Serves as a monomer or building block for creating organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags and molecular probes for diagnostic and research applications.
• Catalyst Ligand Development: The quinoline structure can be functionalized to create novel ligands for transition metal catalysis.
• Academic & Contract Research: Essential reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic chemistry projects.

Basic Information

Item	Details
Product Name	7,8-Dimethyl-2-(2-Thienyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160261-38-0
Molecular Formula	C₁₇H₁₄ClNOS
Molecular Weight	323.81 g/mol
Synonyms	2-(Thiophen-2-yl)-7,8-dimethylquinoline-4-carbonyl chloride; 7,8-Dimethyl-2-(thiophen-2-yl)quinoline-4-carbonyl chloride; 2-(2-Thienyl)-7,8-dimethyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 7,8-dimethyl-2-(2-thienyl)-; TQCC Intermediate
EINECS	Contact for details

Quality Control

Our 7,8-Dimethyl-2-(2-Thienyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.