Description

2-(4-Ethylphenyl)-7,8-Dimethylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is critical for the synthesis of complex organic molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to build sophisticated quinoline-based molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the quinoline scaffold for biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis Reagent: Employed in organic synthesis for the introduction of the 2-(4-ethylphenyl)-7,8-dimethylquinoline moiety via amide or ester bond formation.
• Ligand and Catalyst Development: Used to create complex ligands for metal catalysis and asymmetric synthesis.
• Fluorescent Probe Synthesis: Acts as a precursor for developing quinoline-based fluorescent dyes and sensors used in bioimaging and diagnostics.

Basic Information

Product Name	2-(4-Ethylphenyl)-7,8-Dimethylquinoline-4-Carbonyl Chloride
CAS No.	1160261-28-8
Molecular Formula	C20H18ClNO
Molecular Weight	323.82 g/mol
Synonyms	4-Carbonyl Chloride-2-(4-ethylphenyl)-7,8-dimethylquinoline; 7,8-Dimethyl-2-(4-ethylphenyl)quinoline-4-carbonyl chloride; 2-(4-Ethylphenyl)-7,8-dimethyl-4-quinolinecarbonyl chloride; Quinoline-4-carbonyl chloride, 2-(4-ethylphenyl)-7,8-dimethyl-; 1160261-28-8
EINECS	Contact for details

Quality Control

Our production of 2-(4-Ethylphenyl)-7,8-Dimethylquinoline-4-Carbonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.