Description

2-(2,5-Dimethyl-3-Thienyl)-6-Methylquinoline-4-Carbonyl Chloride is a high-value, specialized organic intermediate featuring a quinoline core functionalized with a thienyl group and an acid chloride moiety. This compound matters as a critical building block for synthesizing complex molecules, particularly in advanced pharmaceutical research and material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or acting as kinase inhibitors.
• Agrochemical Research: Used to construct novel active ingredients for crop protection products, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers, organic semiconductors, or liquid crystals.
• Chemical Synthesis: Versatile acylating agent for introducing the quinoline-thiophene scaffold into more complex molecular architectures in organic chemistry.
• Dye & Pigment Industry: Potential intermediate for creating novel colorants and fluorescent markers due to its conjugated quinoline system.

Basic Information

Product Name	2-(2,5-Dimethyl-3-Thienyl)-6-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160260-82-1
Molecular Formula	C18H16ClNOS
Molecular Weight	329.84 g/mol
Synonyms	6-Methyl-2-(2,5-dimethyl-3-thienyl)quinoline-4-carbonyl chloride; 2-(2,5-Dimethylthiophen-3-yl)-6-methylquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(2,5-dimethyl-3-thienyl)-6-methyl-; 1160260-82-1; 2-(2,5-Dimethyl-3-thienyl)-6-methyl-4-quinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dimethyl-3-Thienyl)-6-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.