Description

2-{[3-(Trifluoromethyl)Benzyl]Oxy}Benzoyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive benzoyl chloride functional group and trifluoromethyl-substituted aromatic system. This compound is critically important for its role in the synthesis of complex bioactive molecules, where it serves as a key building block for introducing specific aromatic ether and amide linkages. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in developing new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-inflammatory drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized aromatic compounds used in electronic display technologies.
• Polymer Modification Agent: Employed to introduce specific aromatic side chains into polymer backbones to alter material properties like thermal stability and solubility.
• Organic Synthesis Reagent: Functions as an acylating agent in research-scale organic synthesis for creating esters, amides, and other derivatives under controlled conditions.
• Chemical Biology Probe Development: Utilized in crafting molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	2-{[3-(Trifluoromethyl)Benzyl]Oxy}Benzoyl Chloride
CAS No.	1160260-62-7
Molecular Formula	C15H10ClF3O2
Molecular Weight	314.69 g/mol
Synonyms	2-[(3-Trifluoromethylbenzyl)oxy]benzoyl chloride; 2-[[[3-(Trifluoromethyl)phenyl]methyl]oxy]benzoyl chloride; 2-((3-(Trifluoromethyl)benzyl)oxy)benzoyl chloride; 2-Hydroxybenzoic acid, 3-(trifluoromethyl)benzyl ester, chloride; o-[(α,α,α-Trifluoro-m-tolyl)methoxy]benzoyl chloride; Benzoyl chloride, 2-[[[3-(trifluoromethyl)phenyl]methyl]oxy]-; 1160260-62-7
EINECS	Contact for details

Quality Control

Our 2-{[3-(Trifluoromethyl)Benzyl]Oxy}Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.