Description

5-Chloro-2-[(4-Fluorobenzyl)Oxy]Benzoyl Chloride is a high-value, multi-functional chemical intermediate essential for advanced organic synthesis. Its core value lies in its dual reactive sites—the benzoyl chloride and the halogenated aromatic ring—which enable precise, sequential functionalization to build complex molecular architectures. This compound is critically needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients, particularly in the synthesis of novel heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, anti-inflammatory agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized aromatic cores used in electronic display technologies.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating high-performance polymers with specific thermal or chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical synthesis projects requiring precise aromatic functionalization.
• Research & Development: A versatile tool in academic and industrial R&D labs for exploring new chemical reactions and creating libraries of compounds for screening.

Basic Information

Product Name	5-Chloro-2-[(4-Fluorobenzyl)Oxy]Benzoyl Chloride
CAS No.	1160260-10-5
Molecular Formula	C14H9Cl2FO2
Molecular Weight	307.13 g/mol
Synonyms	5-Chloro-2-[(4-fluorobenzyl)oxy]benzoyl chloride; 2-(4-Fluorobenzyloxy)-5-chlorobenzoyl chloride; 5-Chloro-2-((4-fluorobenzyl)oxy)benzoyl chloride; Benzoyl chloride, 5-chloro-2-[(4-fluorophenyl)methoxy]-; (5-Chloro-2-{[(4-fluorophenyl)methyl]oxy}phenyl)methanone chloride
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-2-[(4-Fluorobenzyl)Oxy]Benzoyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications, and our quality system is designed to meet the rigorous demands of global industrial and research customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.