Description

5-Bromo-2-[(2-Fluorobenzyl)Oxy]Benzoyl Chloride CAS NO 1160260-02-5 is a high-purity, advanced pharmaceutical intermediate characterized by its reactive benzoyl chloride functional group. This compound is critically important for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of targeted small-molecule therapeutics. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• API Synthesis: Used in the final or penultimate steps of manufacturing complex Active Pharmaceutical Ingredients (APIs).
• Chemical Research: Serves as a versatile reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Development: Employed in scaling up synthetic routes from laboratory to pilot and commercial production scales.
• Custom Synthesis: Foundation for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Product Name	5-Bromo-2-[(2-Fluorobenzyl)Oxy]Benzoyl Chloride
CAS No.	1160260-02-5
Molecular Formula	C14H9BrClFO2
Molecular Weight	343.57 g/mol
Synonyms	5-Bromo-2-[(2-fluorobenzyl)oxy]benzoyl chloride; 2-Fluorobenzyl 5-bromo-2-hydroxybenzoate chloride; 5-Bromo-2-[(2-fluorophenyl)methoxy]benzoyl chloride; Benzoyl chloride, 5-bromo-2-[(2-fluorobenzyl)oxy]-; 1160260-02-5
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-[(2-Fluorobenzyl)Oxy]Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (e.g., nitrogen or argon) when opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.