Description

3-[(4-Fluorobenzyl)Oxy]Benzoyl Chloride is a high-purity, specialized organic intermediate featuring a benzoyl chloride core functionalized with a fluorinated benzyloxy group. This compound is valued for its reactivity as an acylating agent, enabling the efficient synthesis of amides and esters in complex molecular architectures. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a critical intermediate in the manufacture of fluorinated organic compounds for electronic display and lighting applications.
• Polymer Modification: Employed to introduce fluorinated aromatic groups into polymer chains, altering material properties like chemical resistance, thermal stability, and surface energy.
• Custom Synthesis & Contract Research: An essential reagent for custom synthesis houses and CROs (Contract Research Organizations) developing proprietary compounds for clients.
• Chemical Research: Utilized in academic and industrial laboratories for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	3-[(4-Fluorobenzyl)Oxy]Benzoyl Chloride
CAS No.	1160259-91-5
Molecular Formula	C14H10ClFO2
Molecular Weight	264.68 g/mol
Synonyms	3-[(4-Fluorobenzyl)oxy]benzoyl chloride; 4-Fluorobenzyl 3-(chlorocarbonyl)phenyl ether; Benzoic acid, 3-[(4-fluorophenyl)methoxy]-, chloride; m-[(4-Fluorobenzyl)oxy]benzoyl chloride; (3-((4-Fluorobenzyl)oxy)phenyl)(chloro)methanone
EINECS	Contact for details

Quality Control

Our 3-[(4-Fluorobenzyl)Oxy]Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its acid chloride nature and sensitivity to moisture, it should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.