Description

2-(4-Chloro-3-Methylphenoxy)-2-Methylpropanoyl Chloride is a high-purity, reactive acid chloride intermediate essential for advanced organic synthesis. Its core value lies in enabling the efficient, high-yield introduction of the 2-(4-chloro-3-methylphenoxy)-2-methylpropanoyl moiety, a key building block in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to synthesize novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in therapeutic areas requiring phenoxypropanoic acid derivatives.
• Agrochemical Synthesis: Crucial precursor in the manufacturing of herbicides, plant growth regulators, and other crop protection agents.
• Peptide Coupling Reagent: Used as an activating agent for carboxylic acids in peptide bond formation and other amidation reactions.
• Polymer Chemistry: Serves as a monomer or modifying agent for creating specialty polymers with specific functional properties.
• Liquid Crystal & OLED Material Research: Intermediate in the synthesis of advanced organic electronic materials and liquid crystal compounds.
• Dye & Pigment Manufacturing: Used to introduce specific chlorinated phenoxy groups into complex dye and pigment molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new chemical entities.

Basic Information

Item	Detail
Product Name	2-(4-Chloro-3-Methylphenoxy)-2-Methylpropanoyl Chloride
CAS No.	1160257-92-0
Molecular Formula	C11H12Cl2O2
Molecular Weight	247.12 g/mol
Synonyms	2-Methyl-2-(4-chloro-3-methylphenoxy)propanoyl chloride; α,α-Dimethyl-4-chloro-m-tolyloxyacetyl chloride; 4-Chloro-3-methylphenoxyisobutyryl chloride; 2-(4-Chloro-3-methylphenoxy)isobutyryl chloride; Propanoyl chloride, 2-(4-chloro-3-methylphenoxy)-2-methyl-; (4-Chloro-3-methylphenoxy)(isobutyryl) chloride; Isobutyryl chloride, 2-(4-chloro-3-methylphenoxy)-
EINECS	Contact for details

Quality Control

Our 2-(4-Chloro-3-Methylphenoxy)-2-Methylpropanoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliable consistency and traceability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts violently with water, strong bases, and alcohols. Containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and to maintain purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.