Description

2-(2-Chloro-4-Nitrophenoxy)-2-Methylpropanoyl Chloride is a specialized acyl chloride intermediate of significant importance in advanced organic synthesis. This compound is valued for its high reactivity, serving as a key building block for constructing complex molecules with specific functional groups. It is primarily required by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a phenoxy-linked propanoyl moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and plant growth regulators.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for introducing the 2-methylpropanoyl chloride functional group into complex molecular architectures.
• Peptide Mimetics & Linker Chemistry: Facilitates the creation of peptide analogs and the construction of chemical linkers used in bioconjugation and prodrug development.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers and functional materials.

Basic Information

Product Name	2-(2-Chloro-4-Nitrophenoxy)-2-Methylpropanoyl Chloride
CAS No.	1160257-78-2
Molecular Formula	C10H9Cl2NO4
Molecular Weight	278.09 g/mol
Synonyms	2-Methyl-2-[(2-chloro-4-nitrophenoxy)]propanoyl chloride; Propanoyl chloride, 2-[(2-chloro-4-nitrophenoxy)]-2-methyl-; 2-(2-Chloro-4-nitrophenoxy)isobutyryl chloride; 2-(2-Chloro-4-nitro-phenoxy)-2-methyl-propionyl chloride; α-(2-Chloro-4-nitrophenoxy)isobutyryl chloride
EINECS	Contact for details

Quality Control

Our production of 2-(2-Chloro-4-Nitrophenoxy)-2-Methylpropanoyl Chloride adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.