Description

2-(4-Fluorophenoxy)Butanoyl Chloride is a specialized organic intermediate featuring a fluorinated aromatic ether linked to an acid chloride functional group. This molecular architecture makes it a highly reactive and versatile building block for synthesizing more complex molecules. It is primarily utilized by pharmaceutical and agrochemical research & development teams for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorophenoxy moiety for enhanced biological activity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atom improves efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic compounds used in electronic display technologies.
• Polymer Modification Agent: Employed to introduce fluorinated side chains into polymers, altering their surface properties, chemical resistance, and durability.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom chemical synthesis services catering to the needs of biotechnology and material science sectors.
• Research & Development: Essential for medicinal chemistry and process chemistry in both academic and industrial laboratories exploring new chemical entities.

Basic Information

Product Name	2-(4-Fluorophenoxy)Butanoyl Chloride
CAS No.	1160257-66-8
Molecular Formula	C₁₀H₁₀ClFO₂
Molecular Weight	216.64 g/mol
Synonyms	2-(4-Fluorophenoxy)butyryl chloride; Butanoyl chloride, 2-(4-fluorophenoxy)-; 4-Fluorophenoxybutyryl chloride; α-(4-Fluorophenoxy)butyryl chloride; 2-(p-Fluorophenoxy)butyroyl chloride; 1160257-66-8; Butyryl chloride, 2-(4-fluorophenoxy)-
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Fluorophenoxy)Butanoyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure consistent purity and performance for your critical synthesis steps. A detailed Certificate of Analysis (COA) including assay, identity confirmation, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts vigorously with water, strong bases, and alcohols. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.