Description

2-(5-Chloro-2-Thienyl)-6-Ethylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive acid chloride functional group. This compound is critical for the synthesis of complex organic molecules, particularly in medicinal chemistry where it serves as a key building block for active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel quinoline-based drug candidates, particularly for antiviral, anticancer, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the quinoline-thiophene hybrid structure.
• Material Science Precursor: Serves as a monomer or precursor for the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional materials.
• Chemical Synthesis: Employed in organic synthesis for the introduction of the 2-(5-chloro-2-thienyl)-6-ethylquinoline moiety into more complex molecular architectures via amide or ester bond formation.
• Life Science Reagents: Used in the preparation of fluorescent probes, biochemical tools, and other research reagents for diagnostic and biological studies.

Basic Information

Product Name	2-(5-Chloro-2-Thienyl)-6-Ethylquinoline-4-Carbonyl Chloride
CAS No.	1160257-20-4
Molecular Formula	C₁₇H₁₃Cl₂NOS
Molecular Weight	350.26 g/mol
Synonyms	6-Ethyl-2-(5-chloro-2-thienyl)quinoline-4-carbonyl chloride; 2-(5-Chloro-2-thienyl)-6-ethyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(5-chloro-2-thienyl)-6-ethyl-; 1160257-20-4; CTEQ-CC
EINECS	Contact for details

Quality Control

Our 2-(5-Chloro-2-Thienyl)-6-Ethylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flame, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.