Description

8-Chloro-2-(5-Methyl-2-Furyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical building block characterized by its reactive acid chloride group and complex heterocyclic structure. This compound matters for its critical role as a key synthetic intermediate in the development of advanced pharmaceutical compounds and functional materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides due to its bioactive quinoline core.
• Material Science Research: Acts as a building block for creating specialized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Item	Details
Product Name	8-Chloro-2-(5-Methyl-2-Furyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160256-88-1
Molecular Formula	C16H9Cl2NO2
Molecular Weight	334.15 g/mol
Synonyms	8-Chloro-2-(5-methylfuran-2-yl)quinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 8-chloro-2-(5-methyl-2-furanyl)-; 1160256-88-1; 8-Chloro-2-(5-methyl-2-furyl)-4-quinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-(5-Methyl-2-Furyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.