Description

2-(1,3-Benzodioxol-5-Yl)-7-Chloro-8-Methylquinoline-4-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride functional group. This compound is critical for the synthesis of complex molecules, offering a versatile building block for constructing quinoline-based scaffolds with specific substitution patterns. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the quinoline core structure.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Functions as an acylating agent in multi-step organic synthesis to introduce complex quinoline moieties.

Basic Information

Product Name	2-(1,3-Benzodioxol-5-Yl)-7-Chloro-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160256-75-6
Molecular Formula	C19H11Cl2NO3
Molecular Weight	372.20 g/mol
Synonyms	7-Chloro-8-methyl-2-(1,3-benzodioxol-5-yl)quinoline-4-carbonyl chloride; 2-(Benzo[d][1,3]dioxol-5-yl)-7-chloro-8-methylquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(1,3-benzodioxol-5-yl)-7-chloro-8-methyl-; CAS 1160256-75-6
EINECS	Contact for details

Quality Control

Our production of 2-(1,3-Benzodioxol-5-Yl)-7-Chloro-8-Methylquinoline-4-Carbonyl Chloride adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.