Description

2-(1,3-Benzodioxol-5-Yl)-8-Chloroquinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate with a complex heterocyclic structure. This compound is critical for advanced organic synthesis, particularly in constructing novel molecular scaffolds with targeted biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel quinoline-based drug candidates for therapeutic areas such as oncology, infectious diseases, and CNS disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a precursor for creating specialized ligands, catalysts, or functional monomers for advanced polymers.
• Academic & R&D: Employed in medicinal chemistry and organic synthesis research to explore new chemical reactions and structure-activity relationships (SAR).
• Fluorescent Probe Synthesis: The quinoline moiety makes it a potential starting material for synthesizing fluorescent dyes and molecular probes used in bio-imaging and diagnostics.

Basic Information

Product Name	2-(1,3-Benzodioxol-5-Yl)-8-Chloroquinoline-4-Carbonyl Chloride
CAS No.	1160256-73-4
Molecular Formula	C17H9Cl2NO3
Molecular Weight	358.17 g/mol
Synonyms	8-Chloro-2-(1,3-benzodioxol-5-yl)quinoline-4-carbonyl chloride; 2-(Benzo[d][1,3]dioxol-5-yl)-8-chloroquinoline-4-carbonyl chloride; 8-Chloro-2-(3,4-methylenedioxyphenyl)quinoline-4-carbonyl chloride; 1160256-73-4; Quinoline-4-carbonyl chloride, 2-(1,3-benzodioxol-5-yl)-8-chloro-; AKOS026714004
EINECS	Contact for details

Quality Control

Our production of 2-(1,3-Benzodioxol-5-Yl)-8-Chloroquinoline-4-Carbonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.