Description

8-Chloro-2-(2,5-Dimethoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical building block designed for advanced synthesis. This compound matters for its role as a critical intermediate in the development of complex organic molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to construct novel quinoline-based structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-infective properties.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge-transport layers.
• Ligand Synthesis: Utilized in the preparation of complex ligands for catalysis and coordination chemistry, where the chlorocarbonyl group offers a versatile handle for further functionalization.
• Fluorescent Probe Development: Acts as a core structure for synthesizing fluorescent dyes and molecular probes used in biochemical sensing and bioimaging.
• Academic & Contract Research: Essential for medicinal chemistry programs and synthetic methodology research in universities and contract research organizations (CROs).

Basic Information

Item	Details
Product Name	8-Chloro-2-(2,5-Dimethoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160256-54-1
Molecular Formula	C19H15Cl2NO3
Molecular Weight	376.24 g/mol
Synonyms	8-Chloro-2-(2,5-dimethoxyphenyl)quinoline-4-carbonyl chloride; 8-Chloro-2-(2,5-dimethoxyphenyl)-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 8-chloro-2-(2,5-dimethoxyphenyl)-; 1160256-54-1
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-(2,5-Dimethoxyphenyl)Quinoline-4-Carbonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.