Description

8-Chloro-2-(2,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive carbonyl chloride group and complex heterocyclic structure. This compound matters for its critical role as a versatile building block in the synthesis of advanced organic molecules, enabling the introduction of the quinoline pharmacophore. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the biological activity of the quinoline scaffold.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes due to its derivatizable functional groups.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical companies offering bespoke synthesis services for client-specific molecular targets.

Basic Information

Product Name	8-Chloro-2-(2,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160256-46-1
Molecular Formula	C19H13Cl2NO
Molecular Weight	342.22 g/mol
Synonyms	8-Chloro-2-(2,4-dimethylphenyl)quinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 8-chloro-2-(2,4-dimethylphenyl)-; 2-(2,4-Dimethylphenyl)-8-chloroquinoline-4-carbonyl chloride; 8-Chloro-2-(2,4-xylyl)quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-(2,4-Dimethylphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.