Description

2-(4-Butylphenyl)-8-Chloroquinoline-4-Carbonyl Chloride is a high-purity, reactive organic intermediate of significant importance in advanced chemical synthesis. This compound matters because it serves as a critical building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the quinoline scaffold's bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced organic electronic materials, such as OLEDs and sensors.
• Ligand and Catalyst Development: The chloroquinoline and carbonyl chloride functionalities make it a valuable starting point for creating novel chelating ligands and organocatalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent tags, photoaffinity labels, and other molecular probes for biological research.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-(4-Butylphenyl)-8-Chloroquinoline-4-Carbonyl Chloride
CAS No.	1160256-26-7
Molecular Formula	C20H17Cl2NO
Molecular Weight	358.26 g/mol
Synonyms	8-Chloro-2-(4-butylphenyl)quinoline-4-carbonyl chloride; 2-(4-Butylphenyl)-8-chloro-4-quinolinecarbonyl chloride; 8-Chloro-2-(p-butylphenyl)-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 8-chloro-2-[4-(butyl)phenyl]-; 1160256-26-7; 2-(4-n-Butylphenyl)-8-chloroquinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 2-(4-Butylphenyl)-8-Chloroquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems and is supported by a comprehensive Certificate of Analysis (COA). Certificates of Analysis (COA) are available upon request and detail key parameters including purity (HPLC), identity (IR, NMR), and impurity profiles to meet the exacting requirements of research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.