Description

7-Chloro-2-(3-Isobutoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate designed for advanced synthesis. Its core value proposition lies in its reactive acid chloride group and complex quinoline-based structure, enabling the construction of sophisticated molecules with targeted properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it serves as a critical building block for active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation pesticides, herbicides, and fungicides, leveraging its quinoline scaffold for biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent for creating advanced polymers, liquid crystals, or organic electronic materials with specific optical or electronic properties.
• Chemical Biology Probe Development: Employed to create tagged or modified molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic & Industrial R&D: Utilized in exploratory chemistry for discovering new reactions and building complex heterocyclic libraries for high-throughput screening.

Basic Information

Product Name	7-Chloro-2-(3-Isobutoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride
CAS No.	1160256-00-7
Molecular Formula	C22H19Cl2NO2
Molecular Weight	400.30 g/mol
Synonyms	4-Quinolinecarbonyl chloride, 7-chloro-2-[3-(2-methylpropoxy)phenyl]-8-methyl-; 7-Chloro-2-(3-isobutoxyphenyl)-8-methyl-4-quinolinecarbonyl chloride; 2-(3-Isobutoxyphenyl)-7-chloro-8-methylquinoline-4-carbonyl chloride; 7-Chloro-8-methyl-2-(3-isobutoxyphenyl)quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 7-Chloro-2-(3-Isobutoxyphenyl)-8-Methylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support development projects with custom purity grades, including standard, high-purity, and research-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.