Description

2-(3-Butoxyphenyl)-8-Chloroquinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate characterized by its quinoline core and acid chloride functionality. This compound is critical for the synthesis of advanced pharmaceutical agents and functional materials, offering a versatile building block for introducing complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and anti-infective research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its chloroquinoline structure.
• Material Science Research: Serves as a precursor for creating functional dyes, ligands for metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Biology Probes: Utilized in the design of fluorescent probes and enzyme inhibitors for biochemical research.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized chemical products.

Basic Information

Product Name	2-(3-Butoxyphenyl)-8-Chloroquinoline-4-Carbonyl Chloride
CAS No.	1160255-94-6
Molecular Formula	C20H17Cl2NO2
Molecular Weight	374.26 g/mol
Synonyms	8-Chloro-2-(3-butoxyphenyl)quinoline-4-carbonyl chloride; 2-(3-Butoxyphenyl)-8-chloro-4-quinolinecarbonyl chloride; 8-Chloro-2-(3-butoxyphenyl)-4-quinolinecarbonyl chloride; 1160255-94-6; 2-(3-Butoxyphenyl)-8-chloroquinoline-4-carboxylic acid chloride; 8-Chloro-2-(3-butoxyphenyl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-(3-Butoxyphenyl)-8-Chloroquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening and stored separately from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.