Description

8-Chloro-2-(4-Isobutoxyphenyl)Quinoline-4-Carbonyl Chloride is a high-purity, bifunctional organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its dual reactive sites—the acid chloride and the chloro-quinoline moiety—which enable its use as a versatile building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry research targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents, such as herbicides and fungicides, leveraging the quinoline scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds due to its conjugated quinoline structure.
• Custom Chemical Synthesis: Provides a versatile scaffold for contract research organizations (CROs) and CDMOs to build custom, complex molecules for client projects.

Basic Information

Product Name	8-Chloro-2-(4-Isobutoxyphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160255-90-2
Molecular Formula	C21H17Cl2NO2
Molecular Weight	386.27 g/mol
Synonyms	8-Chloro-2-(4-isobutoxyphenyl)quinoline-4-carbonyl chloride; 2-(4-Isobutoxyphenyl)-8-chloroquinoline-4-carbonyl chloride; 8-Chloro-2-[4-(2-methylpropoxy)phenyl]-4-quinolinecarbonyl chloride; Quinoline-4-carbonyl chloride, 8-chloro-2-[4-(2-methylpropoxy)phenyl]-; 1160255-90-2
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-(4-Isobutoxyphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.