Description

2-(5-Chloro-2-Thienyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is a high-value, reactive organic intermediate primarily used in advanced chemical synthesis. This compound matters because it serves as a critical building block for constructing complex heterocyclic molecules, enabling the development of novel materials and active pharmaceutical ingredients (APIs). It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise and reliable synthetic intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, particularly for therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its unique thienyl-quinoline structure for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials, such as OLEDs or conductive polymers.
• Ligand Synthesis: Acts as a starting material for the preparation of specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: Utilized in the design of quinoline-derived fluorescent markers and sensors for biochemical and diagnostic applications.
• Academic & Industrial R&D: A vital reagent for exploratory chemistry in both university laboratories and corporate research centers focusing on heterocyclic chemistry.

Basic Information

Product Name	2-(5-Chloro-2-Thienyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride
CAS No.	1160254-85-2
Molecular Formula	C₁₇H₁₁Cl₂NOS
Molecular Weight	356.25 g/mol
Synonyms	6,8-Dimethyl-2-(5-chloro-2-thienyl)quinoline-4-carbonyl chloride; 2-(5-Chlorothiophen-2-yl)-6,8-dimethylquinoline-4-carbonyl chloride; 4-Chlorocarbonyl-2-(5-chloro-2-thienyl)-6,8-dimethylquinoline; Quinoline-4-carbonyl chloride, 2-(5-chloro-2-thienyl)-6,8-dimethyl-; 1160254-85-2
EINECS	Contact for details

Quality Control

Our 2-(5-Chloro-2-Thienyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.