Description

2-(5-Ethyl-2-Thienyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is a high-value, specialized organic intermediate featuring a quinoline core functionalized with a thienyl group and an acid chloride moiety. This compound matters as a critical building block for the synthesis of complex molecules, particularly in advanced pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or oncology.
• Agrochemical Synthesis: Used in research and development for creating new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced organic electronic materials, such as organic semiconductors or light-emitting materials.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for catalysis or as a scaffold for metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create fluorescent tags or bioactive probes for studying biological processes and target identification.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular architecture.

Basic Information

Product Name	2-(5-Ethyl-2-Thienyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride
CAS No.	1160254-83-0
Molecular Formula	C₁₈H₁₆ClNOS
Molecular Weight	329.84 g/mol
Synonyms	6,8-Dimethyl-2-(5-ethyl-2-thienyl)quinoline-4-carbonyl chloride; 2-(5-Ethylthiophen-2-yl)-6,8-dimethylquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(5-ethyl-2-thienyl)-6,8-dimethyl-; 1160254-83-0; ETDQ-CC; 2-(5-Ethyl-2-thienyl)-6,8-dimethyl-4-quinolinecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-(5-Ethyl-2-Thienyl)-6,8-Dimethylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flame, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.