Description

6,8-Dimethyl-2-(2-Thienyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate characterized by its quinoline core functionalized with a thienyl group and an acid chloride moiety. This compound is of significant value for its role as a key building block in the synthesis of complex organic molecules, particularly in advanced pharmaceutical research and material science. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting neurological disorders or as kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides where the quinoline-thiophene scaffold may confer specific biological activity.
• Material Science: Acts as a monomer or functionalization agent in the creation of organic semiconductors, luminescent materials, or metal-organic frameworks (MOFs).
• Chemical Synthesis: Employed in organic chemistry laboratories for constructing complex heterocyclic systems via amide bond formation or further derivatization of the acid chloride group.
• Dye & Pigment Industry: Utilized as a starting material for synthesizing novel quinoline-based dyes and pigments with specific optical properties.

Basic Information

Product Name	6,8-Dimethyl-2-(2-Thienyl)Quinoline-4-Carbonyl Chloride
CAS No.	1160254-79-4
Molecular Formula	C₁₆H₁₂ClNOS
Molecular Weight	301.79 g/mol
Synonyms	2-(Thiophen-2-yl)-6,8-dimethylquinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 6,8-dimethyl-2-(2-thienyl)-; 6,8-Dimethyl-2-(thiophen-2-yl)quinoline-4-carbonyl chloride; 2-(2-Thienyl)-6,8-dimethyl-4-quinolinecarbonyl chloride; 6,8-Dimethyl-2-thiophen-2-yl-quinoline-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 6,8-Dimethyl-2-(2-Thienyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.